Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 17/20 | 0.42 |
| ▸ | EED | O75530 | 2/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21862149 | 1.00 | UGT8 (0.42) | UGT8EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21813545 | 0.91 | EED (0.45) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21813548 | 0.91 | EED (0.45) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL30845409 | 0.91 | EED (0.45) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21813815 | 0.90 | UGT8 (0.42) | UGT8 | |
| SCHEMBL21813813 | 0.90 | UGT8 (0.42) | UGT8 | |
| SCHEMBL21813767 | 0.90 | UGT8 (0.42) | UGT8 | |
| SCHEMBL30845110 | 0.90 | UGT8 (0.48) | UGT8EEDRBBP4SUZ12EZH2 | |
| SCHEMBL21862150 | 0.88 | UGT8 (0.46) | UGT8EEDRBBP4SUZ12EZH2 | |
| SCHEMBL30845059 | 0.88 | UGT8 (0.46) | UGT8EEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |