Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 19/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813607 | 1.00 | UGT8 (0.55) | UGT8HTR1ADRD2HTR2A | |
| SCHEMBL21813894 | 0.91 | UGT8 (0.55) | UGT8 | |
| SCHEMBL21813340 | 0.87 | UGT8 (0.71) | UGT8 | |
| SCHEMBL21813341 | 0.87 | UGT8 (0.71) | UGT8 | |
| SCHEMBL21813991 | 0.82 | UGT8 (0.80) | UGT8 | |
| SCHEMBL21813677 | 0.81 | UGT8 (0.44) | UGT8 | |
| SCHEMBL21813414 | 0.79 | UGT8 (0.80) | UGT8 | |
| SCHEMBL21813700 | 0.79 | UGT8 (0.70) | UGT8 | |
| SCHEMBL21862117 | 0.79 | UGT8 (0.71) | UGT8 | |
| SCHEMBL21813679 | 0.78 | UGT8 (0.42) | UGT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |