SCHEMBL30845019

SCHEMBL30845019

CNC(=O)c1csc2c(C(F)(F)F)cc(N3CCC(OCC(O)CN4CCOCC4)CC3)nc12

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UGT8 Q16880 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21813928 1.00 UGT8 (0.70) UGT8
SCHEMBL21813774 0.89 UGT8 (0.65) UGT8
SCHEMBL30844912 0.89 UGT8 (0.65) UGT8
SCHEMBL21814019 0.88 UGT8 (0.68) UGT8
SCHEMBL21813952 0.88 UGT8 (0.65) UGT8
SCHEMBL30845055 0.86 UGT8 (0.69) UGT8
SCHEMBL21813933 0.86 UGT8 (0.69) UGT8
SCHEMBL30845415 0.84 UGT8 (0.70) UGT8
SCHEMBL21813564 0.82 UGT8 (1.00) UGT8
SCHEMBL21813733 0.82 UGT8 (0.82) UGT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423711-B Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof 建新公司 2024-03-15 CN claimed
CN-113423711-B Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof 建新公司 2024-03-15 CN disclosed