Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 19/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30845024 | 1.00 | UGT8 (0.51) | UGT8IKBKETBK1 | |
| SCHEMBL30844938 | 1.00 | UGT8 (0.51) | UGT8IKBKETBK1 | |
| SCHEMBL30844918 | 0.93 | UGT8 (0.51) | UGT8 | |
| SCHEMBL30845260 | 0.93 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21862610 | 0.93 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813674 | 0.90 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813507 | 0.90 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813899 | 0.90 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813766 | 0.90 | UGT8 (0.51) | UGT8 | |
| SCHEMBL21813656 | 0.90 | UGT8 (0.51) | UGT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |