Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813408 | 0.83 | NPC1 (0.37) | NPC1 | |
| SCHEMBL78659 | 0.81 | HPGD (0.52) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL15771046 | 0.81 | BACE1 (0.43) | HPGDGPR119RECQLEPHX1KDM1A | |
| SCHEMBL78365 | 0.80 | HPGD (0.55) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL77972 | 0.78 | RECQL (0.56) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL22835640 | 0.77 | HPGD (0.49) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL27145651 | 0.77 | HPGD (0.49) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL1576027 | 0.76 | HPGD (0.50) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL2149148 | 0.76 | HPGD (0.50) | PRMT5WDR77HPGDGPR119RECQL | |
| SCHEMBL21722940 | 0.75 | HPGD (0.45) | HPGDGPR119RECQLEPHX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |