Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814084 | 1.00 | POLB (0.32) | POLBPKMNOTUM | |
| SCHEMBL21814209 | 0.78 | NOTUM (0.33) | NOTUM | |
| SCHEMBL21813409 | 0.74 | UGT8 (0.47) | — | |
| SCHEMBL30845432 | 0.72 | UGT8 (0.43) | NOTUM | |
| SCHEMBL21813648 | 0.72 | UGT8 (0.43) | NOTUM | |
| SCHEMBL21813883 | 0.67 | NOTUM (0.33) | NOTUM | |
| SCHEMBL21814039 | 0.67 | KDM4E (0.41) | POLBNOTUM | |
| SCHEMBL21813864 | 0.61 | CFTR (0.37) | POLBPKM | |
| SCHEMBL21813802 | 0.61 | UGT8 (0.42) | — | |
| SCHEMBL30845399 | 0.61 | CFTR (0.37) | POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |