Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 19/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828487 | 0.99 | UGT8 (0.57) | UGT8KDM4E | |
| SCHEMBL21813861 | 0.85 | KDM4E (0.59) | UGT8KDM4E | |
| SCHEMBL30845417 | 0.85 | KDM4E (0.59) | UGT8KDM4E | |
| SCHEMBL21862130 | 0.85 | UGT8 (0.67) | UGT8 | |
| SCHEMBL30845425 | 0.85 | UGT8 (0.67) | UGT8 | |
| SCHEMBL21828531 | 0.84 | KDM4E (0.58) | UGT8KDM4E | |
| SCHEMBL21862572 | 0.83 | UGT8 (0.65) | UGT8KDM4E | |
| SCHEMBL30845109 | 0.83 | UGT8 (0.65) | UGT8KDM4E | |
| SCHEMBL21813426 | 0.81 | UGT8 (0.66) | UGT8KDM4E | |
| SCHEMBL21814207 | 0.81 | UGT8 (0.67) | UGT8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |