Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265301 | 1.00 | MAPT (0.71) | MAPTLMNAALDH1A1P2RY1KDM4E | |
| SCHEMBL21611354 | 0.85 | MAPT (0.75) | MAPTLMNAALDH1A1P2RY1KDM4E | |
| SCHEMBL30845454 | 0.78 | MAPT (0.45) | MAPTALDH1A1EGFRCSF1RBRAF | |
| SCHEMBL29265304 | 0.78 | MAPT (0.45) | MAPTALDH1A1EGFRCSF1RBRAF | |
| SCHEMBL15169670 | 0.74 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4EEGFR | |
| Ammonia Solution, Strong SCHEMBL29265302 | 0.73 | MAPT (0.57) | MAPTLMNAALDH1A1P2RY1KDM4E | |
| SCHEMBL21611461 | 0.73 | MAPT (0.57) | MAPTLMNAALDH1A1TP53EGFR | |
| SCHEMBL6491051 | 0.72 | MAPT (0.56) | MAPTLMNAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1307813 | 0.72 | MAPT (0.59) | MAPTALDH1A1P2RY1KDM4ECYP1A2 | |
| SCHEMBL21611362 | 0.71 | MAPT (0.56) | MAPTLMNAALDH1A1TP53EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118021833-A | Intestinal metabolite regulator and medicine containing regulator | 华南农业大学 | 2024-05-14 | — | — | CN | disclosed |