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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30845654

Cc1cc(S(=O)(=O)Nc2cscn2)cnc1N(C)C1CCN(Cc2ccccc2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.82

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SCN8A Q9UQD0 20/20 0.82
▸ SCN1A P35498 19/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21773261 1.00 SCN8A (0.82) SCN8ASCN1A
SCHEMBL30845646 0.94 SCN8A (0.92) SCN8ASCN1A
SCHEMBL21773103 0.94 SCN8A (0.92) SCN8ASCN1A
SCHEMBL21772989 0.90 SCN8A (1.00) SCN8ASCN1A
SCHEMBL30845639 0.90 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21772990 0.90 SCN8A (1.00) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL19613963 0.87 SCN8A (0.88) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL19613960 0.87 SCN8A (0.88) SCN8ASCN1A
SCHEMBL21773250 0.86 SCN8A (1.00) SCN8ASCN1A
SCHEMBL30845616 0.86 SCN8A (1.00) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638898-B Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2024-04-09 — — CN disclosed