SCHEMBL30845671

SCHEMBL30845671

CN(c1cnc(S(=O)(=O)Nc2cscn2)cc1C(F)(F)F)[C@H]1CCN(Cc2ccccc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21773289 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21773208 1.00 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21773259 0.96 SCN8A (1.00) SCN8ASCN1A
Trifluoroacetic Acid SCHEMBL21773062 0.92 SCN8A (0.93) SCN8ASCN1A
SCHEMBL21773144 0.90 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21773148 0.90 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21773147 0.89 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19612908 0.89 SCN8A (1.00) SCN8ASCN1A
SCHEMBL19612909 0.89 SCN8A (1.00) SCN8ASCN1A
SCHEMBL21773092 0.88 SCN8A (1.00) SCN8ASCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638898-B Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2024-04-09 CN disclosed