Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675739 | 1.00 | KDM4E (0.48) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL31527805 | 0.98 | KDM4E (0.47) | KDM4EKMT2AMEN1NOS3NOS1 | |
| Trifluoroacetic Acid SCHEMBL30845714 | 0.85 | PTGS1 (0.41) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL2643186 | 0.81 | UHRF1 (0.48) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL1464557 | 0.79 | UHRF1 (0.46) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL8434248 | 0.79 | UHRF1 (0.46) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL1824530 | 0.79 | UHRF1 (0.46) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL3439204 | 0.78 | UHRF1 (0.45) | KDM4EKMT2AMEN1NOS3NOS1 | |
| SCHEMBL2642943 | 0.78 | UHRF1 (0.45) | KDM4EKMT2AMEN1NOS3NOS1 | |
| Fluoride SCHEMBL27839384 | 0.78 | UHRF1 (0.45) | KDM4EKMT2AMEN1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109563-A1 | SPIRO-HYDANTOIN DERIVATIVE EXHIBITING ADAMTS-4 INHIBITORY ACTIVITY, AND USE THEREOF | 서울대학교병원 | 2025-05-30 | — | — | WO | claimed |
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |