Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21594794 | 1.00 | TSHR (0.52) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL31275102 | 1.00 | TSHR (0.52) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL23706440 | 1.00 | TSHR (0.52) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL1759110 | 0.95 | — | — | |
| SCHEMBL1759112 | 0.95 | — | — | |
| SCHEMBL9188658 | 0.91 | TSHR (0.63) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL2401513 | 0.91 | TSHR (0.63) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL2401509 | 0.91 | TSHR (0.63) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL16371432 | 0.84 | TSHR (0.50) | TSHRAKT1LMNAALDH1A1EPHX2 | |
| SCHEMBL23434850 | 0.84 | TSHR (0.44) | TSHRAKT1LMNAALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190391092-A1 | METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS) | Oregon Institute of Science and Medicine | 2019-12-26 | — | — | US | disclosed |
| US-PP21289-P3 | Hop plant named ‘HBC 394’ | Hop Breeding Company, L.L.C. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090193555-P1 | Hop plant named 'HBC 394' | HOP BREEDING COMPANY, LLC | 2009-07-30 | — | — | US | disclosed |
| US-PP15663-P2 | Hop plant named ‘YCR Accession No. 4’ | SELECT BOTANICALS GROUP, L.L.C. (US) | 2005-03-15 | — | — | US | disclosed |
| US-PP12213-P2 | Hop plant named ‘YCR Accession No. 14’ | YAKIMA CHIEF RANCHES, INC. | 2001-11-20 | — | — | US | disclosed |