Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND2 | P30279 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205998 | 1.00 | FEN1 (0.41) | FEN1ENPP1ADORA1KDM4EALDH1A1 | |
| SCHEMBL30940172 | 0.79 | CDC7 (0.40) | FEN1ENPP1ADORA1KDM4EALDH1A1 | |
| SCHEMBL25130651 | 0.79 | CDC7 (0.40) | FEN1ENPP1ADORA1KDM4EALDH1A1 | |
| SCHEMBL5871967 | 0.76 | FEN1 (0.54) | FEN1KDM4EALDH1A1MAPTTHRB | |
| SCHEMBL20674217 | 0.72 | NOTUM (0.40) | FEN1KDM4EMAPTKDM4A | |
| SCHEMBL30448847 | 0.71 | MAPT (0.37) | KDM4EMAPTNPSR1L3MBTL1CA12 | |
| SCHEMBL3093956 | 0.71 | MAPT (0.37) | KDM4EMAPTNPSR1L3MBTL1CA12 | |
| SCHEMBL24393387 | 0.69 | ENPP1 (0.43) | FEN1ENPP1ADORA1KDM4EALDH1A1 | |
| SCHEMBL13242249 | 0.69 | — | — | |
| SCHEMBL29248810 | 0.68 | PRMT5 (0.38) | ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843633-A | Sulfoximine compounds, pharmaceutical compositions and uses thereof | 上海海和药物研究开发股份有限公司 | 2024-04-09 | — | — | CN | disclosed |