Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798804 | 0.86 | TDP1 (0.58) | HSP90AA1ESR2TDP1POLBRAB9A | |
| SCHEMBL29171880 | 0.86 | TDP1 (0.58) | HSP90AA1ESR2TDP1POLBRAB9A | |
| SCHEMBL29171929 | 0.85 | CHEK2 (0.46) | HSP90AA1ESR2TDP1POLBRAB9A | |
| SCHEMBL30848087 | 0.85 | CHEK2 (0.46) | HSP90AA1ESR2TDP1POLBRAB9A | |
| SCHEMBL30798987 | 0.85 | TLR8 (0.42) | HSP90AA1ESR2TDP1TLR8TLR7 | |
| SCHEMBL8264538 | 0.85 | HSP90AA1 (0.53) | HSP90AA1ESR2TDP1TLR8TLR7 | |
| SCHEMBL30798800 | 0.84 | TLR8 (0.43) | HSP90AA1ESR2TDP1TLR8TLR7 | |
| SCHEMBL30798862 | 0.84 | TLR8 (0.39) | HSP90AA1ESR2TDP1TLR8TLR7 | |
| SCHEMBL30799136 | 0.84 | BRD4 (0.41) | HSP90AA1ESR2TDP1TLR8TLR7 | |
| SCHEMBL29171942 | 0.81 | HDAC6 (0.53) | HSP90AA1ESR2TDP1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585588-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Pharmavan Co., Ltd. (CN) | 2025-07-16 | — | — | EP | disclosed |
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |