Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21196123 | 0.88 | ERN1 (0.34) | ERN1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL31459749 | 0.84 | CYP1A2 (0.36) | ERN1CYP3A4MAPT | |
| SCHEMBL25259877 | 0.81 | CA1 (0.37) | ERN1 | |
| SCHEMBL1349494 | 0.81 | CYP3A4 (0.38) | ERN1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL26087630 | 0.81 | CYP3A4 (0.46) | ERN1CYP3A4MAPT | |
| SCHEMBL21195865 | 0.81 | POLB (0.33) | ERN1CYP3A4 | |
| SCHEMBL29344302 | 0.81 | ERN1 (0.31) | ERN1 | |
| SCHEMBL21378953 | 0.80 | ERN1 (0.33) | ERN1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL11763496 | 0.79 | CYP3A4 (0.37) | ERN1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL20975107 | 0.78 | ERN1 (0.30) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |