Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.50 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30850472 | 1.00 | CRBN (0.50) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL30850431 | 1.00 | CRBN (0.50) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL28654926 | 1.00 | CRBN (0.50) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL30850447 | 1.00 | CRBN (0.50) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL23908396 | 0.96 | CRBN (0.52) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL35210249 | 0.93 | CRBN (0.53) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL23908568 | 0.93 | CRBN (0.53) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL30850384 | 0.92 | CRBN (0.49) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL30850394 | 0.92 | CRBN (0.49) | CRBNDDB1GSPT1ALDH1A1CHRM2 | |
| SCHEMBL30850404 | 0.92 | CRBN (0.49) | CRBNDDB1GSPT1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102970-A1 | COMPOUNDS FOR MODULATING SYK ACTIVITY AND E3 UBIQUITIN LIGASE ACTIVITY | Kronos Bio, Inc. (US) | 2024-05-16 | — | — | WO | disclosed |