Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790627 | 0.90 | CRBN (0.57) | CRBNIKZF1IKZF2 | |
| SCHEMBL30270874 | 0.87 | CRBN (0.63) | CRBNIKZF1IKZF2 | |
| SCHEMBL24745083 | 0.87 | CRBN (0.63) | CRBNIKZF1IKZF2 | |
| SCHEMBL25010545 | 0.85 | CRBN (0.60) | CRBNIKZF1IKZF2 | |
| SCHEMBL25010247 | 0.84 | CRBN (0.61) | CRBNIKZF1IKZF2 | |
| SCHEMBL30270865 | 0.84 | CRBN (0.61) | CRBNIKZF1IKZF2 | |
| SCHEMBL22557008 | 0.83 | CRBN (0.69) | CRBNIKZF1IKZF2 | |
| SCHEMBL29876913 | 0.83 | CRBN (0.69) | CRBNIKZF1IKZF2 | |
| SCHEMBL25010377 | 0.83 | CRBN (0.57) | CRBNIKZF1IKZF2 | |
| SCHEMBL30270762 | 0.83 | CRBN (0.57) | CRBNIKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881668-A | Compound based on isoindoline substituted glutarimide skeleton and application thereof | 标新生物医药科技(上海)有限公司 | 2024-04-12 | — | — | CN | disclosed |