Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968405 | 1.00 | HTR2A (0.45) | HTR2AHTR2CHTR2BAURKAKDR | |
| SCHEMBL24968228 | 0.84 | AURKA (0.37) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL30851115 | 0.84 | AURKA (0.37) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL21031170 | 0.82 | AURKA (0.40) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL24968232 | 0.82 | ATM (0.40) | AURKAKDRAURKBATMTAAR1 | |
| SCHEMBL30851096 | 0.82 | ATM (0.40) | AURKAKDRAURKBATMTAAR1 | |
| SCHEMBL932942 | 0.81 | AURKA (0.39) | AURKAKDRAURKBPIK3R1PIK3CA | |
| SCHEMBL29208803 | 0.81 | AURKA (0.39) | AURKAKDRAURKBPIK3R1PIK3CA | |
| SCHEMBL27233788 | 0.81 | AURKA (0.39) | HTR2AHTR2CAURKAKDRAURKB | |
| SCHEMBL29165939 | 0.79 | PIK3R1 (0.36) | AURKAKDRAURKBKDM4EPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |