Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 8/20 | 0.55 |
| ▸ | CDK2 | P24941 | 8/20 | 0.55 |
| ▸ | CDK1 | P06493 | 7/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.55 |
| ▸ | CDK4 | P11802 | 6/20 | 0.55 |
| ▸ | CCND1 | P24385 | 6/20 | 0.55 |
| ▸ | CCND3 | P30281 | 6/20 | 0.55 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.54 |
| ▸ | CDK9 | P50750 | 6/20 | 0.54 |
| ▸ | CDK7 | P50613 | 5/20 | 0.54 |
| ▸ | CCNH | P51946 | 5/20 | 0.54 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121914 | 0.88 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL30291353 | 0.87 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL31121910 | 0.86 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL27360391 | 0.85 | CCNE1 (0.56) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL30291234 | 0.85 | CCNE1 (0.56) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL30851406 | 0.85 | CDK2 (0.57) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL30291355 | 0.84 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL31121905 | 0.84 | CCNE1 (0.55) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL30291376 | 0.83 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CDK4 | |
| SCHEMBL31121908 | 0.83 | CDK1 (0.59) | CCNE1CDK2CDK1CCNB1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813300-A | Substituted pyrimidinyl-pyrazoles as CDK2 inhibitors | 缆图药品公司 | 2024-04-02 | — | — | CN | disclosed |