Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085994 | 1.00 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3085998 | 1.00 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3086000 | 1.00 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3086506 | 0.92 | NR1I2 (0.35) | KCNH2 | |
| SCHEMBL2453536 | 0.92 | NR1I2 (0.35) | KCNH2 | |
| SCHEMBL3086504 | 0.92 | NR1I2 (0.35) | KCNH2 | |
| SCHEMBL3086503 | 0.92 | NR1I2 (0.35) | KCNH2 | |
| SCHEMBL3076787 | 0.92 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL2456093 | 0.91 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL2456095 | 0.91 | KCNH2 (0.34) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | KCNH2 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.