Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189649 | 1.00 | SLC22A6 (0.37) | SLC22A6GRIA1TP53 | |
| SCHEMBL3421787 | 0.83 | SLC22A6 (0.43) | SLC22A6GRIA1TP53 | |
| SCHEMBL776560 | 0.78 | — | — | |
| SCHEMBL6722136 | 0.78 | SLC22A6 (0.40) | SLC22A6GRIA1TP53 | |
| SCHEMBL27855486 | 0.78 | GRIA1 (0.33) | GRIA1 | |
| SCHEMBL27881836 | 0.76 | SLC22A6 (0.39) | SLC22A6GRIA1 | |
| SCHEMBL27881825 | 0.76 | — | — | |
| SCHEMBL18631405 | 0.74 | GRIA1 (0.31) | GRIA1 | |
| SCHEMBL11151795 | 0.74 | SLC22A6 (0.37) | SLC22A6GRIA1TP53 | |
| SCHEMBL575440 | 0.74 | SLC22A6 (0.37) | SLC22A6GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |