⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312888 | 0.87 | — | — | |
| SCHEMBL14605353 | 0.75 | — | — | |
| Bromide SCHEMBL21176812 | 0.75 | — | — | |
| SCHEMBL12132766 | 0.61 | — | — | |
| SCHEMBL3954056 | 0.61 | — | — | |
| SCHEMBL3256493 | 0.61 | — | — | |
| SCHEMBL13344319 | 0.61 | — | — | |
| SCHEMBL14189197 | 0.61 | — | — | |
| SCHEMBL5200137 | 0.50 | — | — | |
| SCHEMBL7648158 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198471-B2 | 2, 2′-bis (dialkylphosphino) biphenyl compound, production method thereof, and metal complex comprising the compound as ligand | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2012-06-12 | — | — | US | claimed |
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2010-09-16 | — | — | US | claimed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-12041797-B2 | Photoelectric conversion element, device, and power supply module | RICOH COMPANY, LTD. (JP) | 2024-07-16 | — | — | US | disclosed |
| CN-110997686-B | Method for producing 2, 3-biphosphinylpyrazine derivative and method for producing phosphine transition metal complex | 日本化学工业株式会社 | 2023-11-03 | — | — | CN | disclosed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| US-20230221637-A1 | Holographic Recording Materials and Methods of Making Same | UNIV COLORADO REGENTS (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230165978-A1 | Composition and A Method For Diagnosing And Treating Bacterial Infection | Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Limited (HK) | 2023-06-01 | — | — | US | disclosed |
| CN-110709407-B | Method for producing optically active 2, 3-bisphosphinylpyrazine derivative, and method for producing optically active phosphine transition metal complex | 日本化学工业株式会社 | 2022-04-15 | — | — | CN | disclosed |
| US-11021500-B2 | Process for preparing optically active 2,3-bisphosphino-substituted quinoxalines | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-06-01 | — | — | US | disclosed |
| US-20200247833-A1 | METHOD FOR PRODUCING 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, AND METHOD FOR PRODUCING PHOSPHINE TRANSITION METAL COMPLEX | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| EP-1245551-B1 | 1,2-BIS(METHYL(1,1,3,3-TETRAMETHYLBUTYL)-PHOSPHINO)ETHANE, PROCESS FOR THE PREPARATION THEREOF, TRANSITION METAL COMPLEXES CONTAINING THE SAME AS THE LIGAND AND USES THEREOF | NIPPON CHEMICAL IND COMPANY LT (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6603032-B1 | Novel bisphosphine compound having a chiral center on the phosphorus atom, which is suitable as a ligand for an asymmetric catalyst for use in asymmetric hydrogenation, this bisphosphine compound having a given structure | NIPPON CHEMICAL INDUSTRIES CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1245551-A1 | 1,2-BIS(METHYL(1,1,3,3-TETRAMETHYLBUTYL)-PHOSPHINO)ETHANE, PROCESS FOR THE PREPARATION THEREOF, TRANSITION METAL COMPLEXES CONTAINING THE SAME AS THE LIGAND AND USES THEREOF | NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0997470-A1 | Optically active bisphosphinomethanes and their rhodium and copper complexes for catalytic asymmetric syntheses | Chiba University (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0571515-B1 | CHIRAL PHOSPHINITE-BORANES, THEIR PREPARATION AND USE | ELF AQUITAINE (FR) | 1995-11-29 | — | — | EP | disclosed |
| US-5434285-A | WHICH ARE STRUCTURALLY DIFFERENT THAN THE PRIOR ART | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1995-07-18 | — | — | US | disclosed |
| EP-0571515-A1 | CHIRAL PHOSPHINITE-BORANES, THEIR PREPARATION AND USE. | ELF AQUITAINE (FR) | 1993-12-01 | — | — | EP | disclosed |
| US-5264602-A | Chiral phosphinite-boranes, their preparation and uses | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1993-11-23 | — | — | US | disclosed |
| WO-1992014739-A1 | CHIRAL PHOSPHINITE-BORANES, THEIR PREPARATION AND USE | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1992-09-03 | — | — | WO | disclosed |