Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402947 | 1.00 | IRAK4 (0.36) | IRAK4FFAR1RPS6KA3GSK3AGSK3B | |
| SCHEMBL15328646 | 0.90 | IRAK4 (0.34) | IRAK4FFAR1RPS6KA3GSK3AGSK3B | |
| SCHEMBL25314625 | 0.88 | FFAR1 (0.34) | IRAK4FFAR1RPS6KA3GSK3AGSK3B | |
| SCHEMBL15328815 | 0.82 | GSK3A (0.32) | IRAK4FFAR1GSK3AGSK3BUSP30 | |
| SCHEMBL30242559 | 0.82 | CYP4F2 (0.38) | IRAK4GSK3AGSK3BUSP30PDGFRB | |
| SCHEMBL12370610 | 0.82 | CYP4F2 (0.38) | IRAK4GSK3AGSK3BUSP30PDGFRB | |
| SCHEMBL14887165 | 0.79 | IRAK4 (0.39) | IRAK4FFAR1GSK3AGSK3BPDGFRB | |
| SCHEMBL17678304 | 0.79 | IRAK4 (0.46) | IRAK4FFAR1LPLLIPG | |
| SCHEMBL15328506 | 0.79 | FFAR1 (0.34) | IRAK4FFAR1RPS6KA3GSK3AGSK3B | |
| SCHEMBL21026361 | 0.76 | IRAK4 (0.54) | IRAK4FFAR1USP30LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598918-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024073871-A1 | GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-04-11 | — | — | WO | disclosed |