Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.58 |
| ▸ | JAK2 | O60674 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | KIF5B | P33176 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275575 | 0.90 | RET (0.57) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL31275552 | 0.88 | RET (0.59) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL28601255 | 0.84 | RET (0.63) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL28429873 | 0.83 | RET (0.63) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL30239330 | 0.82 | RET (0.62) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL22041657 | 0.82 | RET (0.62) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL24409106 | 0.82 | RET (0.54) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL30728233 | 0.82 | RET (0.55) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL24409213 | 0.82 | RET (0.55) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL28438659 | 0.80 | RET (0.66) | RETJAK2FLT3KIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574201-B | Arylamine compound, pharmaceutical composition containing arylamine compound, and preparation method and application of arylamine compound | 四川科伦博泰生物医药股份有限公司 | 2024-04-19 | — | — | CN | disclosed |