Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.59 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276550 | 1.00 | ERN1 (0.59) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL565717 | 0.85 | ERN1 (0.64) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL1478225 | 0.84 | ERN1 (0.47) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL30826221 | 0.81 | ERN1 (0.62) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL911855 | 0.81 | ERN1 (0.44) | ERN1ALDH1A1TSHRPTPRFAOX1 | |
| SCHEMBL5552745 | 0.79 | ERN1 (0.61) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL1888264 | 0.79 | ERN1 (0.61) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL19792605 | 0.79 | ERN1 (0.43) | ERN1PRKDCALDH1A1TSHRKDM4E | |
| SCHEMBL28057376 | 0.79 | ERN1 (0.43) | ERN1ALDH1A1TSHRPTPRFAOX1 | |
| SCHEMBL16797103 | 0.79 | ERN1 (0.40) | ERN1PRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| CN-119497713-A | USP1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |