Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605525 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2RIPK1ANO1KMT2AL3MBTL1 | |
| Ether SCHEMBL26646426 | 0.90 | BRD4 (0.43) | SMN1; SMN2RIPK1ANO1KDM4ESSTR4 | |
| SCHEMBL13962868 | 0.84 | CNR2 (0.46) | KMT2ASSTR4P2RX7NPC1RAB9A | |
| SCHEMBL6415070 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2RIPK1ANO1KMT2ATRPV1 | |
| SCHEMBL22832228 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2RIPK1ANO1L3MBTL1KDM4E | |
| SCHEMBL6417499 | 0.81 | ANO1 (0.47) | SMN1; SMN2RIPK1ANO1KITTRPV1 | |
| SCHEMBL30695551 | 0.80 | PLK1 (0.46) | SMN1; SMN2KMT2AL3MBTL1KDM4EKIT | |
| SCHEMBL7045677 | 0.80 | HDAC1 (0.46) | SMN1; SMN2KMT2AL3MBTL1KDM4EKIT | |
| SCHEMBL8568914 | 0.80 | PLK1 (0.46) | SMN1; SMN2KMT2AL3MBTL1KDM4EKIT | |
| SCHEMBL31426964 | 0.79 | ANO1 (0.40) | SMN1; SMN2RIPK1ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |