Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 3/20 | 0.54 |
| ▸ | TNF | P01375 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21837746 | 1.00 | MDM4 (0.55) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL21837748 | 1.00 | MDM4 (0.55) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL30854430 | 0.93 | TLR2 (0.57) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL22109013 | 0.93 | TLR2 (0.57) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL22108925 | 0.93 | TLR2 (0.57) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL31688883 | 0.92 | MDM4 (0.54) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL8892048 | 0.92 | MDM4 (0.60) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL23811012 | 0.90 | TLR2 (0.61) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL21837710 | 0.90 | TLR2 (0.61) | MDM4TP53TLR2TNFCASP3 | |
| SCHEMBL31697677 | 0.90 | TLR2 (0.61) | MDM4TP53TLR2TNFCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-118184532-A | Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same | 中外制药株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-113454058-B | Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same | 中外制药株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |