Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | CPT2 | P23786 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HMGCR | P04035 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | BHMT | Q93088 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48109 | 1.00 | KDM4E (0.65) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL10887191 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL10887236 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL8581488 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL9819340 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| Hydrochloric Acid SCHEMBL5406891 | 0.97 | KDM4E (0.70) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL4624372 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL6733907 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| SCHEMBL11439787 | 0.97 | KDM4E (0.62) | KDM4EFFAR1CPT2TDP1HMGCR | |
| Water SCHEMBL14109826 | 0.94 | KDM4E (0.59) | KDM4EFFAR1CPT2TDP1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290333-A | Novel inhibitors of gonorrhoeae-specific tyrosine phosphatase (LYP) | 普渡研究基金会 | 2024-07-05 | — | — | CN | disclosed |
| CN-115461056-B | Inhibitors of Lebaba-specific tyrosine phosphatase (LYP) | 普渡研究基金会 | 2024-04-16 | — | — | CN | disclosed |