Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854969 | 0.95 | KDM4E (0.45) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30855004 | 0.94 | KDM4E (0.48) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30854973 | 0.93 | KDM4E (0.47) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30244963 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30245327 | 0.86 | MAPT (0.49) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30245739 | 0.85 | AGXT (0.46) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30245029 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL29194759 | 0.85 | AGXT (0.47) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL30854952 | 0.82 | MAPT (0.44) | KDM4EALDH1A1MEN1HPGDCASP1 | |
| SCHEMBL29194839 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1MEN1HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |