Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609576 | 1.00 | HTR2A (0.71) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| SCHEMBL11609582 | 1.00 | HTR2A (0.71) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| Hydrochloric Acid SCHEMBL11611171 | 0.98 | HTR2A (0.69) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| SCHEMBL5268995 | 0.85 | HTR2A (0.69) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| SCHEMBL29171814 | 0.85 | HTR2A (0.69) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| Hydrochloric Acid SCHEMBL10921173 | 0.84 | HTR2A (0.67) | HTR2AIDO1ADRA1ATAAR1AOC3 | |
| SCHEMBL1740902 | 0.83 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL31545209 | 0.83 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL1740903 | 0.83 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL3460220 | 0.83 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073601-A2 | ARIADNE AND ANALOGS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROMUSCLAR DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-04-04 | — | — | WO | disclosed |