Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15287245 | 0.74 | POLB (0.55) | POLBLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL27621311 | 0.73 | POLB (0.53) | POLBLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL12149758 | 0.70 | POLB (0.50) | POLBLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL24759505 | 0.70 | POLB (0.50) | POLBLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL28202038 | 0.68 | IDH1 (0.44) | LMNAALDH1A1IDH1KDM4EGAA | |
| SCHEMBL27229506 | 0.67 | POLB (0.67) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL13440540 | 0.67 | NOTUM (0.47) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7215257 | 0.66 | POLB (0.46) | POLBLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL4381208 | 0.65 | ANPEP (0.45) | POLBLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4375863 | 0.65 | POLB (0.62) | POLBLMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |