Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383298 | 0.85 | MAPK8 (0.37) | PRKCIDDB1CRBNMAPTKDM4E | |
| SCHEMBL26423115 | 0.81 | MEN1 (0.36) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31482837 | 0.80 | MAPK8 (0.39) | MAPTHTTADORA2AADORA2B | |
| SCHEMBL31482839 | 0.80 | MAPK8 (0.39) | MAPTHTTADORA2AADORA2B | |
| SCHEMBL26262738 | 0.78 | HTR1D (0.38) | MAPTALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL10075621 | 0.77 | PRKCI (0.39) | PRKCIDDB1CRBNMAPTKDM4E | |
| SCHEMBL31482861 | 0.77 | DDB1 (0.35) | DDB1CRBNADORA2A | |
| SCHEMBL3655093 | 0.77 | PRKCI (0.41) | PRKCIDDB1CRBNMAPTKDM4E | |
| SCHEMBL15081375 | 0.76 | SCN9A (0.40) | PRKCIDDB1CRBNMAPTKDM4E | |
| SCHEMBL3376205 | 0.75 | ADORA2A (0.59) | PRKCIDDB1CRBNMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894878-A | Aromatic amide derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |
| WO-2024078569-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-18 | — | — | WO | disclosed |