Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204348 | 0.87 | GRM4 (0.44) | NT5EPOLBMAPK8DYRK3PIM1 | |
| SCHEMBL28888965 | 0.82 | MAPK8 (0.41) | MAPK8MAPTGAASMN1; SMN2NPSR1 | |
| SCHEMBL15730377 | 0.81 | SSTR4 (0.48) | POLBMAPK8DYRK3PIM1MAPK9 | |
| SCHEMBL29195479 | 0.80 | POLB (0.46) | POLBMAPK8DYRK3PIM1MAPK9 | |
| SCHEMBL30856615 | 0.80 | POLB (0.46) | POLBMAPK8DYRK3PIM1MAPK9 | |
| SCHEMBL23467043 | 0.80 | NT5E (0.38) | NT5EMAPK8MAPTALDH1A1MEN1 | |
| SCHEMBL13106482 | 0.77 | MAPK8 (0.41) | POLBMAPK8MAPTL3MBTL1LMNA | |
| SCHEMBL25446307 | 0.76 | NT5E (0.38) | NT5EKDM4EALDH1A1MEN1HTT | |
| SCHEMBL1336984 | 0.75 | ADORA2A (0.59) | MAPK8MAPTKDM4ENPC1GRM4 | |
| SCHEMBL15730345 | 0.75 | POLB (0.51) | POLBMAPTKDM4EGRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |