Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 20/20 | 0.75 |
| ▸ | VEGFA | P15692 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556076 | 1.00 | EPAS1 (0.75) | EPAS1VEGFA | |
| SCHEMBL30856810 | 0.91 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL16555668 | 0.91 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL16560819 | 0.86 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560936 | 0.86 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL24317771 | 0.84 | EPAS1 (0.85) | EPAS1VEGFA | |
| SCHEMBL16556029 | 0.82 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL19870977 | 0.82 | EPAS1 (0.70) | EPAS1VEGFA | |
| SCHEMBL16560977 | 0.80 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16555737 | 0.79 | EPAS1 (0.71) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |