Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 20/20 | 0.66 |
| ▸ | VEGFA | P15692 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ARNT | P27540 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16555888 | 1.00 | EPAS1 (0.66) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16555528 | 0.90 | EPAS1 (0.66) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL21005536 | 0.83 | EPAS1 (0.49) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16555738 | 0.82 | EPAS1 (0.68) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL30605959 | 0.82 | EPAS1 (0.68) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16556057 | 0.81 | EPAS1 (0.66) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16555409 | 0.80 | EPAS1 (0.64) | EPAS1VEGFA | |
| SCHEMBL16555475 | 0.80 | EPAS1 (0.68) | EPAS1VEGFA | |
| SCHEMBL24317169 | 0.80 | EPAS1 (0.70) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL19870988 | 0.80 | EPAS1 (0.80) | EPAS1VEGFACYP2C9ARNTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |