Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20073067 | 0.93 | MAPT (0.62) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30950765 | 0.88 | TDP1 (0.53) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28124476 | 0.88 | TDP1 (0.53) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL37039 | 0.88 | TDP1 (0.53) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11441066 | 0.87 | PARP15 (0.53) | CA1CA2SMN1; SMN2MAPTGAA | |
| SCHEMBL12446490 | 0.86 | TDP1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTESR2 | |
| SCHEMBL10329337 | 0.86 | TDP1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTESR2 | |
| Bicarbonate SCHEMBL6905502 | 0.86 | TDP1 (0.52) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| Water SCHEMBL2784554 | 0.86 | TDP1 (0.52) | CA1CA2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29228932 | 0.86 | TDP1 (0.52) | CA1CA2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050538-A1 | PLASTIC-DEGRADING ENZYME VARIANTS AND THEIR USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-03-07 | — | — | WO | disclosed |