SCHEMBL30857744

SCHEMBL30857744

COC(=O)C1=C(OS(=O)(=O)C(F)(F)F)CCC2(CC2)C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15538726 0.95
SCHEMBL1677588 0.86 CXCR2 (0.30) CXCR2
SCHEMBL1864213 0.86 MAPT (0.36)
SCHEMBL1528651 0.85 PTPN1 (0.31)
SCHEMBL19839335 0.84
SCHEMBL31756622 0.84
SCHEMBL31756346 0.83 NPSR1 (0.30)
SCHEMBL19839439 0.81
SCHEMBL22325429 0.79
SCHEMBL1956595 0.79 CXCR2 (0.32) CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024067818-A1 CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF 江苏恒瑞医药股份有限公司 2024-04-04 WO disclosed