Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 7/20 | 0.61 |
| ▸ | BCL2 | P10415 | 11/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857524 | 0.93 | BCL2L1 (0.71) | BCL2L1BCL2MMP14ADAMTS5BCL2L2 | |
| SCHEMBL28447129 | 0.89 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL21751591 | 0.89 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL30857743 | 0.86 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL2972697 | 0.84 | BCL2L1 (0.85) | BCL2L1BCL2BCL2L2 | |
| Oxalic Acid SCHEMBL29832219 | 0.82 | BCL2L1 (0.82) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL23164961 | 0.80 | BCL2L1 (0.51) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL21751607 | 0.80 | BCL2L1 (0.51) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL28990477 | 0.79 | BCL2 (0.49) | BCL2L1BCL2 | |
| SCHEMBL30542888 | 0.78 | BCL2L1 (0.53) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |