Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 8/20 | 0.59 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657751 | 0.86 | CREBBP (0.59) | CREBBPBRPF1GSK3BTSHRDAO | |
| SCHEMBL30858659 | 0.86 | CREBBP (0.59) | CREBBPBRPF1GSK3BTSHRDAO | |
| SCHEMBL15243711 | 0.81 | CREBBP (0.58) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL14765190 | 0.81 | CREBBP (0.58) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL14765075 | 0.78 | CREBBP (0.54) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL17928722 | 0.77 | CREBBP (0.53) | CREBBPBRPF1GSK3BTSHRMEN1 | |
| SCHEMBL13802283 | 0.76 | CREBBP (0.56) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL13802289 | 0.76 | CREBBP (0.56) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL7668762 | 0.75 | CREBBP (1.00) | CREBBPBRPF1GSK3BTSHRBRD4 | |
| SCHEMBL1101924 | 0.75 | CREBBP (1.00) | CREBBPBRPF1GSK3BTSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580621-A2 | T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS | The Broad Institute, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| CN-120091815-A | T-type voltage-gated calcium channel enhancer | 广泛研究所股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2024050312-A2 | T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS | THE BROAD INSTITUTE, INC. (US) | 2024-03-07 | — | — | WO | disclosed |