SCHEMBL30858697

SCHEMBL30858697

O=C(NCc1nnn[nH]1)n1ccnc1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808774 0.72 KMT2A (0.41) MAPT
SCHEMBL24000994 0.72 NAMPT (0.47) MAPT
SCHEMBL23455649 0.71 SMN1; SMN2 (0.54) MAPT
SCHEMBL3120859 0.70 CYP1A2 (0.32)
SCHEMBL6255257 0.70 SMN1; SMN2 (0.44) MAPT
SCHEMBL5632317 0.69
SCHEMBL2789986 0.69 NPSR1 (0.39) MAPT
SCHEMBL10048209 0.69 KMT2A (0.50) MAPT
SCHEMBL19851470 0.69 SMN1; SMN2 (0.40)
SCHEMBL31737685 0.69 CYP11B1 (0.46) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618952-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-09-24 EP disclosed
WO-2024108198-A2 METHODS OF TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-05-23 WO disclosed