Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.73 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221845 | 1.00 | HDAC6 (0.73) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL13365424 | 0.90 | HDAC6 (0.67) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL14461305 | 0.88 | HDAC1 (0.72) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL4929814 | 0.87 | HDAC1 (0.71) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL4866671 | 0.87 | HDAC1 (0.71) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL2641714 | 0.87 | HDAC1 (0.71) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL2641717 | 0.87 | HDAC1 (0.81) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL30858826 | 0.85 | HDAC1 (0.81) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL20509078 | 0.85 | HDAC1 (0.76) | HDAC6HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL13991492 | 0.85 | HDAC1 (0.72) | HDAC6HDAC1HDAC2HDAC3HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886748-A | Quinoline amino acid conjugate and preparation method and application thereof | 天津科技大学 | 2024-04-16 | — | — | CN | disclosed |