Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229269 | 0.81 | MAPT (0.41) | MAPTTSHRKDM4E | |
| SCHEMBL2666937 | 0.78 | HRH3 (0.47) | MAPTTSHR | |
| SCHEMBL31229231 | 0.76 | TSHR (0.42) | MAPTTSHRKDM4E | |
| SCHEMBL19296321 | 0.74 | GAA (0.39) | MAPTKDM4E | |
| SCHEMBL30858987 | 0.74 | MAPT (0.40) | MAPTTSHRKDM4E | |
| SCHEMBL30858920 | 0.74 | MAPT (0.54) | MAPTTSHRKDM4E | |
| SCHEMBL29261611 | 0.72 | MAPT (0.39) | MAPTTSHR | |
| SCHEMBL30858932 | 0.72 | MAPT (0.39) | MAPTTSHR | |
| SCHEMBL31229226 | 0.71 | MAPT (0.47) | MAPTTSHRKDM4E | |
| SCHEMBL30858944 | 0.71 | MAPT (0.47) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024230578-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-11-14 | — | — | WO | disclosed |
| CN-117946138-A | And ring nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |