Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.66 |
| ▸ | JAK2 | O60674 | 11/20 | 0.66 |
| ▸ | JAK3 | P52333 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474766 | 1.00 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24474800 | 1.00 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL29431184 | 1.00 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24474761 | 1.00 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL26969049 | 1.00 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24474783 | 0.96 | JAK1 (0.69) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL29431074 | 0.96 | JAK1 (0.69) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24474962 | 0.96 | JAK1 (0.69) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24474765 | 0.93 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL24475203 | 0.93 | JAK1 (0.66) | JAK1JAK2JAK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269736-B | Amide compound, pharmaceutical composition and application thereof | 科辉智药(深圳)新药研究中心有限公司 | 2024-02-02 | — | — | CN | disclosed |