SCHEMBL30859583

SCHEMBL30859583

CC(C)(C)OC(=O)N1CCC(n2ccc(N[C@@H]3CCC(=O)NC3=O)cc2=O)CC1

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 17/20 0.65
CRBN Q96SW2 17/20 0.65
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859555 1.00 DDB1 (0.65) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL30257373 0.82 DDB1 (0.62) DDB1CRBNMAPTALDH1A1
SCHEMBL27039808 0.82 DDB1 (0.62) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL25631810 0.81 DDB1 (0.60) DDB1CRBNMAPT
SCHEMBL23538658 0.81 DDB1 (0.69) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL21965415 0.81 DDB1 (0.67) DDB1CRBN
SCHEMBL23538462 0.81 DDB1 (0.77) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL23539242 0.81 DDB1 (0.77) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL21965763 0.81 DDB1 (0.77) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL29946906 0.81 DDB1 (0.77) DDB1CRBNKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024073475-A9 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) 2025-04-24 WO disclosed
WO-2024073475-A1 CEREBLON LIGANDS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed