Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.44 |
| ▸ | INSR | P06213 | 5/20 | 0.44 |
| ▸ | IGF1R | P08069 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860355 | 0.95 | EGFR (0.49) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26906717 | 0.92 | EGFR (0.56) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30860243 | 0.92 | EGFR (0.51) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26906997 | 0.91 | EGFR (0.51) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30860236 | 0.89 | EGFR (0.55) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26906511 | 0.87 | EGFR (0.58) | EGFRMETALKINSRIGF1R | |
| SCHEMBL26906601 | 0.86 | EGFR (0.62) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30860392 | 0.86 | EGFR (0.47) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30860383 | 0.85 | EGFR (0.55) | EGFRMETALKINSRIGF1R | |
| SCHEMBL30860402 | 0.85 | EGFR (0.51) | EGFRMETALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |