Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 5/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228058 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL20324247 | 0.85 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL30860931 | 0.84 | ATR (0.41) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL27227802 | 0.84 | ATR (0.41) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL31602907 | 0.84 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL23478362 | 0.84 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL29780245 | 0.83 | ATR (0.40) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL23461124 | 0.83 | ATR (0.40) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL27228501 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1POLBLMNA | |
| SCHEMBL25324455 | 0.80 | RET (0.42) | CYP4F2CYP4A11ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |