Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718490 | 1.00 | PI4KA (0.37) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL614642 | 0.81 | PTGER3 (0.36) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL30251519 | 0.81 | PTGER3 (0.36) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL30861129 | 0.79 | ADORA2A (0.39) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL27228033 | 0.79 | ADORA2A (0.39) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL27228198 | 0.79 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL30860818 | 0.79 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL30855850 | 0.78 | GAA (0.35) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL459070 | 0.78 | IDO1 (0.42) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL15209635 | 0.78 | GAA (0.35) | PI4KAPI4K2BPI4K2API4KBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |