⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321 | 1.00 | — | — | |
| SCHEMBL8531822 | 1.00 | — | — | |
| SCHEMBL10631564 | 1.00 | — | — | |
| SCHEMBL28183870 | 1.00 | — | — | |
| SCHEMBL17629825 | 1.00 | — | — | |
| SCHEMBL8560847 | 1.00 | — | — | |
| SCHEMBL28321570 | 1.00 | — | — | |
| SCHEMBL158268 | 1.00 | — | — | |
| SCHEMBL25358537 | 0.71 | — | — | |
| Fluoride SCHEMBL2005440 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617843-B2 | Human broadly neutralizing antibodies against the membrane-proximal external region of HIV Env for vaccine design and intervention | THE SCRIPPS RESEARCH INSTITUTE (US) | 2026-05-05 | — | — | US | disclosed |
| US-20240124560-A1 | HUMAN BROADLY NEUTRALIZING ANTIBODIES AGAINST THE MEMBRANE-PROXIMAL EXTERNAL REGION OF HIV ENV FOR VACCINE DESIGN AND INTERVENTION | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-18 | — | — | US | disclosed |