SCHEMBL30861990

SCHEMBL30861990

CONC(=O)Nc1ccc(-c2sc3c(c2CCl)c(=O)n(-c2ccc(OC)nn2)c(=O)n3Cc2c(F)cccc2F)cc1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.84
KCNH2 Q12809 11/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779991 1.00 GNRHR (0.84) GNRHRKCNH2
SCHEMBL30861967 0.93 GNRHR (0.85) GNRHRKCNH2
SCHEMBL777764 0.92 GNRHR (0.83) GNRHRKCNH2
Relugolix SCHEMBL29386968 0.91 GNRHR (1.00) GNRHRKCNH2
Relugolix SCHEMBL778416 0.91 GNRHR (1.00) GNRHRKCNH2
SCHEMBL779129 0.91 GNRHR (0.78) GNRHRKCNH2
SCHEMBL778278 0.90 GNRHR (0.79) GNRHRKCNH2
SCHEMBL777819 0.90 GNRHR (0.82) GNRHRKCNH2
SCHEMBL29743161 0.90 GNRHR (0.87) GNRHRKCNH2
SCHEMBL780125 0.89 GNRHR (0.80) GNRHRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024069492-A1 PROCESSES FOR THE PREPARATION AND MANUFACTURE OF RELUGOLIX MACFARLAN SMITH LIMITED (GB) 2024-04-04 WO disclosed