Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 4/20 | 0.54 |
| ▸ | PIP5K1C | O60331 | 10/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028510 | 0.93 | ITK (0.48) | ITKPIP5K1CNPC1RAB9AGFER | |
| SCHEMBL24670928 | 0.92 | ITK (0.53) | ITKPIP5K1CRIPK1MET | |
| SCHEMBL12027720 | 0.92 | ITK (0.53) | ITKPIP5K1CCDK5CDK5R1NPC1 | |
| SCHEMBL29990522 | 0.92 | ITK (0.53) | ITKPIP5K1CRIPK1MET | |
| SCHEMBL12028506 | 0.92 | ITK (0.49) | ITKPIP5K1CNPC1RAB9AGFER | |
| SCHEMBL12027721 | 0.91 | ITK (0.62) | ITKPIP5K1CCNR1RIPK1HPGD | |
| SCHEMBL12027722 | 0.90 | ITK (0.52) | ITKPIP5K1C | |
| SCHEMBL29989984 | 0.88 | ITK (0.51) | ITKPIP5K1C | |
| SCHEMBL24671251 | 0.88 | ITK (0.51) | ITKPIP5K1C | |
| SCHEMBL24671204 | 0.87 | ITK (0.49) | ITKPIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916231-A | Compounds for inhibiting or degrading target proteins, compositions comprising the same, methods of making and methods of using the same | 纽力克斯治疗公司 | 2024-04-19 | — | — | CN | disclosed |